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FEATURES

FAMILY

peptidase S1 family

DESCRIPTION

Also known as FA11_HUMAN, F11. Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Homodimer; disulfide-linked. Forms a heterodimer with SERPINA5. After activation the heavy and light chains are also linked by a disulfide bond.

Also known as FA11_HUMAN, F11. Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Homodimer; disulfide-linked. Forms a heterodimer with SERPINA ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

F11

Coagulation factor XI

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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