FEATURES

FAMILY

sauvagine/corticotropin-releasing factor/urotensin I family

DESCRIPTION

Also known as CRF_HUMAN, CRH. Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Interacts (via C-terminus) with CRFR1 (via N-terminal extracellular domain).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CRH

Corticoliberin

CRH

Molecular Synopsis