FEATURES

FAMILY

methyl-coenzyme M reductase beta subunit family

DESCRIPTION

Also known as MCRB_METBF, mcrB. Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

EXTERNAL LINKS

uniprot
enzyme classification

mcrB

Mutations

Mutation(s) distribution

Mutations table