FEATURES

FAMILY

DESCRIPTION

Also known as KCNAS_DROME, Sh, mns. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Forms rapidly inactivating tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient and may contribute to A-type currents (PubMed:2448636). Plays a role in the regulation of sleep need or efficiency (PubMed:15858564). Plays a role in sexual behavior, where it is imortant for male sex discrimination (PubMed:22292044). Homotetramer or heterotetramer of potassium channel proteins.

EXTERNAL LINKS

Sh

Potassium voltage-gated channel protein Shaker

Sh

Molecular Synopsis