FEATURES

DESCRIPTION

Also known as C4BPA_MOUSE, C4bpa, C4bp. Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component. Homoheptamer; not covalently linked. Mouse lacks the beta chain of C4BP.

EXTERNAL LINKS

uniprot
enzyme classification

C4bpa

C4b-binding protein

C4bpa

Molecular Synopsis