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FEATURES

FAMILY

AP endonuclease 2 family

DESCRIPTION

Also known as END4_ECOLI, nfo. Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. Monomer.

Also known as END4_ECOLI, nfo. Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal su ...

EXTERNAL LINKS

uniprot
enzyme classification

nfo

Endonuclease 4

Molecular Synopsis

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