FEATURES

FAMILY

DESCRIPTION

Also known as GLO2_ECOLI, gloB, yafR. Type II glyoxalase that catalyzes the hydrolysis of (R)-S-lactoylglutathione to (R)-lactate and glutathione (PubMed:25670698, PubMed:17196158). Is more efficient than the isozyme GloC, and plays a major contribution to methylglyoxal (MG) detoxification in E.coli (PubMed:25670698). The two isoenzymes have additive effects and ensure maximal MG degradation (PubMed:25670698). Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

gloB

Hydroxyacylglutathione hydrolase GloB

gloB

Molecular Synopsis