FEATURES

FAMILY

DESCRIPTION

Also known as NUOI_ECOLI, nuoI. NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

nuoI

NADH-quinone oxidoreductase subunit I

Mutations

Mutation(s) distribution

Mutations table

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