FEATURES

FAMILY

Potassium channel inhibitor kappa-KTx family

DESCRIPTION

Also known as KKX21_OPIMA, KKX21. OmTx1 decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 17% and Kv1.2/KCNA2 by 12% as well as human Kv1.3/KCNA3 by 24%., OmTx2 decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 8% and Kv1.2/KCNA2 by 10% as well as human Kv1.3/KCNA3 by 36%. Also alters glucose-induced insulin release from pancreatic islets.

EXTERNAL LINKS

uniprot
enzyme classification

KKX21

Potassium channel toxin kappa-KTx 2.2

KKX21

Molecular Synopsis