FEATURES

FAMILY

DESCRIPTION

Also known as H2A_SPHLA, H2A. Antimicrobial peptide with potent activity against some Gram-positive and Gram-negative bacteria (PubMed:30044391). Does not permeabilize membrane, but internalizes into bacterial cells and alter specific gene expression involved in bacterial resistance mechanisms (PubMed:30044391). Has the ability to agglutinate E.coli, and lipid vesicles (PubMed:30044391). Shows a weak hemolytic activity, and is not cytotoxic to monocytes (PubMed:30044391).

EXTERNAL LINKS

uniprot
enzyme classification

H2A

Buforin-2

H2A

Structural Ligandability

Domains Chains

Distribution