FEATURES

FAMILY

DESCRIPTION

Also known as E8_VAR67, E8R. Early protein packaged into virion cores. May play a role in the biogenesis of the viral factories by recruiting and wrapping these DNA replication sites in endoplasmic reticulum derived membranes. Later in infection, phosphorylation of E8R by the late viral kinase F10L might decrease E8R DNA-binding ability and trigger ER membranes disassembly. Binds DNA in vitro (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

E8R

Protein E8

E8R

Molecular Synopsis