FEATURES

FAMILY

DESCRIPTION

Also known as ZP3_MOUSE, Zp3, Zp-3, Zpc. Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers. Interacts with ZP1 and ZP2.

Also known as ZP3_MOUSE, Zp3, Zp-3, Zpc. Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents ...

EXTERNAL LINKS

uniprot
enzyme classification

Zp3

Mutations

Mutation(s) distribution

Mutations table