FEATURES

DESCRIPTION

Also known as HPR_BACSU, hpr, catA, scoC. Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing oligopeptide permease operons (appABCDF and oppABCDF), thereby preventing uptake of oligopeptides required for initiation of sporulation. Acts with SinR as a corepressor of epr expression. Homodimer. Interacts with SinR.

EXTERNAL LINKS

uniprot
enzyme classification

hpr

HTH-type transcriptional regulator Hpr

hpr

Molecular Synopsis