FEATURES

DESCRIPTION

Also known as ABRA_ABRPR, ABRA. The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4, 324 of 28S rRNA. Abrin-a is more toxic than ricin., The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis. Disulfide-linked dimer of A and B chains.

EXTERNAL LINKS

uniprot
enzyme classification

ABRA

Mutations

Mutation(s) distribution

Mutations table