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FAMILY

WD repeat SEC12 family

DESCRIPTION

Also known as SEC12_YEAST, SEC12, SED2. Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein SAR1. Required for autophagy.

Also known as SEC12_YEAST, SEC12, SED2. Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER. This function involves the cytoplasmic domai ...

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uniprot
enzyme classification

SEC12

Guanine nucleotide-exchange factor SEC12

Mutations

Mutation(s) distribution

Mutations table

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