FEATURES

FAMILY

sodium:solute symporter (SSF) (TC 2.A.21) family

DESCRIPTION

Also known as SC5A1_HUMAN, SLC5A1, NAGT, SGLT1. Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC5A1

Sodium/glucose cotransporter 1

SLC5A1

Molecular Synopsis