FEATURES

FAMILY

herpesviridae polymerase accessory protein family

DESCRIPTION

Also known as VPAP_HCMVA, UL44. Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization. Forms homodimers. Interacts with host SMARCB1. Interacts with host NCL/nucleolin; this interaction is important for the organization of proteins within viral replication compartments. Interacts with UL112/UL113; this interaction is necessary for efficient viral DNA replication. Interacts with UL84. Interacts with the uracil DNA glycosylase UL114. Interacts with the DNA polymerase catalytic subunit UL54.

EXTERNAL LINKS

uniprot
enzyme classification

UL44

Mutations

Mutation(s) distribution

Mutations table