FEATURES

DESCRIPTION

Also known as GATA1_CHICK, GATA1, ERYF1. Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Interacts with EP300; the interaction enhances transcriptional activity as a direct result of acetylation.

EXTERNAL LINKS

uniprot
enzyme classification

GATA1

Erythroid transcription factor

Mutations

Mutation(s) distribution

Mutations table

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