FEATURES

FAMILY

class-I pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as ATTY_HUMAN, TAT. Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TAT

Tyrosine aminotransferase

TAT

Molecular Synopsis