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FEATURES

FAMILY

biopterin-dependent aromatic amino acid hydroxylase family

DESCRIPTION

Also known as TPH1_HUMAN, TPH1, TPH, TPRH, TRPH. Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TPH1

Tryptophan 5-hydroxylase 1

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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