FEATURES

FAMILY

DESCRIPTION

Also known as LECF_ALEAU, LECF. Lectin that specifically binds to L-fucose (PubMed:2193930, PubMed:2666154, PubMed:7397108, PubMed:18493851, PubMed:21945439, PubMed:27650323, PubMed:28800497, PubMed:14503859, PubMed:12732625). Has strongest preference for the alpha-1, 6-fucosylated chain (core fucose) on glycoproteins among alpha-1, 2-, alpha-1, 3-, alpha-1, 4-, and alpha-1, 6-fucosylated chains (PubMed:17383961, PubMed:19109923, PubMed:20798114, PubMed:22226468). Might play a role in the differentiation of the fruiting body (PubMed:2193930). Exhibits antifungal activity against Mucor racemosus and thus could act as an antifungal protein in natural ecosystems (PubMed:22738968). Forms homodimers (PubMed:2193930, PubMed:7397108, PubMed:20798114, PubMed:12732625). The two AAL monomers are associated via interactions between N-terminal and C-terminal peptides (PubMed:12732625). Tyr-7 interacts via aromatic ring stacking with its counterpart on the other monomer, whereas Ser-284 interacts via hydrogen bonding with Asp-264 on the other monomer (PubMed:12732625).

Also known as LECF_ALEAU, LECF. Lectin that specifically binds to L-fucose (PubMed:2193930, PubMed:2666154, PubMed:7397108, PubMed:18493851, PubMed:21945439, PubMed:27650323, PubMed:28800497, ...

EXTERNAL LINKS

LECF

Fucose-specific lectin

LECF

Molecular Synopsis