FEATURES

FAMILY

cation transport ATPase (P-type) (TC 3.A.3) family

DESCRIPTION

Also known as PMA2_ARATH, AHA2. The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport (PubMed:10748244, PubMed:12920605, PubMed:27013734). The resulting external acidification and/or internal alkinization may mediate growth responses (PubMed:10748244, PubMed:12920605). Involved in maintaining the membrane potential and delta-pH, together forming the plasma membrane protonmotive force (PMF) required for root and hypocotyl elongation and root tropism (PubMed:22214817, PubMed:24492258). Important for root growth and development during different nitrogen regimes (PubMed:25382626). Forms a functional cation-translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes (PubMed:26071421). Binds to 14-3-3 proteins (PubMed:10593986). The binding is induced by phosphorylation of Thr-947 and it activates the H(+)-ATPase (PubMed:10593986). Interacts (via the R-domain) with PSY1R (via C-terminus) (PubMed:25267325). Part of a functional complex containing PSKR1, BAK1, CNGC17, and AHA (PubMed:26071421). Interacts with CNGC17 and PSKR1 (PubMed:26071421).

EXTERNAL LINKS

AHA2

Mutations

Mutation(s) distribution

Mutations table