FEATURES

FAMILY

DESCRIPTION

Also known as SPEE_HUMAN, SRM, SPS1, SRML1. Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1, 3-diaminopropane. Has extremely low activity towards spermidine. Homodimer or homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRM

Spermidine synthase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation