FEATURES

FAMILY

receptors of complement activation (RCA) family

DESCRIPTION

Also known as CR2_HUMAN, CR2, C3DR. Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047)., (Microbial infection) Acts as a receptor for Epstein-Barr virus. Interacts (via Sushi domain 1 and 2) with C3 (PubMed:11387479, PubMed:21527715). Interacts with CD19 (PubMed:1702139). Part of a complex composed of CD19, CR2/CD21, CD81 and IFITM1/CD225 in the membrane of mature B-cells (PubMed:1383329).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CR2

Mutations

Mutation(s) distribution

Mutations table