FEATURES

FAMILY

DESCRIPTION

Also known as OSM1_YEAST, OSM1. Irreversibly catalyzes the reduction of fumarate to succinate. Together with the second isozyme of soluble fumarate reductase (FRD1), essential for anaerobic growth. Involved in maintaining redox balance during oxygen deficiency conditions. Reduction of fumarate is the main source of succinate during fermentation, and under anaerobic conditions, the formation of succinate is strictly required for the reoxidation of FADH(2).

EXTERNAL LINKS

uniprot
enzyme classification

OSM1

Fumarate reductase 2

OSM1

Molecular Synopsis