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Also known as ODPA_GEOSE, pdhA. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Heterodimer of an alpha and a beta chain.

Also known as ODPA_GEOSE, pdhA. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyr ...

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uniprot
enzyme classification

pdhA

Pyruvate dehydrogenase E1 component subunit alpha

Mutations

Mutation(s) distribution

Mutations table

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