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FEATURES

FAMILY

Cation-dependent O-methyltransferase family

DESCRIPTION

Also known as COMT_RAT, Comt. Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.

Also known as COMT_RAT, Comt. Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain ...

EXTERNAL LINKS

uniprot
enzyme classification

Comt

Catechol O-methyltransferase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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