FEATURES

FAMILY

cyclic nucleotide phosphodiesterase family

DESCRIPTION

Also known as PDE6B_BOVIN, PDE6B, PDEB. Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity). Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity). May participate in processes of transmission and amplification of the visual signal (By similarity). Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.

EXTERNAL LINKS

uniprot
enzyme classification

PDE6B

Rod cGMP-specific 3', 5'-cyclic phosphodiesterase subunit beta

Mutations

Mutation(s) distribution

Mutations table

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