FEATURES

FAMILY

low molecular weight phosphotyrosine protein phosphatase family

DESCRIPTION

Also known as PPAC_HUMAN, ACP1. Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity. Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3. Interacts with EPHA2; dephosphorylates EPHA2. Interacts with EPHB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ACP1

Low molecular weight phosphotyrosine protein phosphatase

ACP1

Molecular Synopsis