FEATURES

DESCRIPTION

Also known as BRD2_HUMAN, BRD2, KIAA9001, RING3. May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. Homodimer. Interacts with E2F1 and with histone H4 acetylated at 'Lys-13'.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

BRD2

Bromodomain-containing protein 2

BRD2

Molecular Synopsis