FEATURES

FAMILY

archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family

DESCRIPTION

Also known as RPB9_YEAST, RPB9. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. Involved in the regulation of transcription elongation. Involved in DNA repair of damage in the transcribed strand. Mediates a transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER). Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.

EXTERNAL LINKS

RPB9

DNA-directed RNA polymerase II subunit RPB9

RPB9

Molecular Synopsis