FEATURES

FAMILY

DESCRIPTION

Also known as CO4A5_HUMAN, COL4A5. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

COL4A5

Collagen alpha-5(IV) chain

COL4A5

Molecular Synopsis