FEATURES

FAMILY

DESCRIPTION

Also known as VATC_YEAST, VMA5, VAT3, VATC. Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C acts as a flexible stator that holds together the catalytic and the membrane sectors of the enzyme. Reversibly leaves the enzyme after glucose depletion, causing the catalytic subcomplex V1 to detach from the V0 section. Binds ATP and is likely to have a specific function in the catalytic activity of the catalytic sector. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d and e). Interacts directly with VMA4.

EXTERNAL LINKS

VMA5

V-type proton ATPase subunit C

3D Viewer

1U7L_A

CAVITIES

STRUCTURE SETTINGS

LIGANDS

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