FEATURES

FAMILY

DESCRIPTION

Also known as L1CAM_HUMAN, L1CAM, CAML1, MIC5. Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. Interacts with SHTN1; the interaction occurs in axonal growth cones (By similarity). Interacts with isoform 2 of BSG (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

L1CAM

Neural cell adhesion molecule L1

Structural Ligandability

Domains Chains

0 chains assessed

1 chain not associated with a domain

L1CAM

Structural Ligandability

Domains Chains

Distribution