FEATURES

FAMILY

purine nucleoside phosphorylase YfiH/LACC1 family

DESCRIPTION

Also known as PURNU_ECOLI, yfiH. Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine (PubMed:31978345). Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (PubMed:31978345). Also has adenosine deaminase activity (PubMed:31978345). May also act as a polyphenol oxidase: able to oxidize syringaldazine and 2, 2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) in vitro (PubMed:16740638). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

yfiH

Mutations

Mutation(s) distribution

Mutations table