FEATURES

FAMILY

DESCRIPTION

Also known as GRM7_RAT, Grm7, Gprc1g, Mglur7. G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits. Homodimer (By similarity). Interacts with PICK1.

EXTERNAL LINKS

uniprot
enzyme classification

Grm7

Metabotropic glutamate receptor 7

Grm7

Molecular Synopsis