FEATURES

FAMILY

DESCRIPTION

Also known as ADDB_HUMAN, ADD2, ADDB. Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. Heterodimer of an alpha and a beta subunit. Found in a complex with ADD2, DMTN and SLC2A1. Interacts with SLC2A1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADD2

Beta-adducin

ADD2

Molecular Synopsis