FEATURES

FAMILY

eukaryotic RPB7/RPC8 RNA polymerase subunit family

DESCRIPTION

Also known as RPC8_YEAST, RPC25. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation. Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. RPC25/RPC8 and RPC17/RPC9 form a Pol III subcomplex.

EXTERNAL LINKS

uniprot
enzyme classification

RPC25

Mutations

Mutation(s) distribution

Mutations table