FEATURES

FAMILY

DESCRIPTION

Also known as HSP80_SOLLC, HSC80. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

HSC80

Heat shock cognate protein 80

HSC80

Structural Ligandability

Domains Chains

Distribution