FEATURES

FAMILY

DESCRIPTION

Also known as GH_MEHV1, gH. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interacts with glycoprotein L (gL); this interaction is necessary for the correct processing and cell surface expression of gH. The heterodimer gH/gL seems to interact with gB trimers during fusion.

EXTERNAL LINKS

uniprot
enzyme classification

gH

Envelope glycoprotein H

gH

Structural Ligandability

Domains Chains

Distribution