FEATURES

FAMILY

DESCRIPTION

Also known as RAD51_CHICK, RAD51A, RAD51. Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange.

EXTERNAL LINKS

uniprot
enzyme classification

RAD51A

DNA repair protein RAD51 homolog 1

RAD51A

Molecular Synopsis