FEATURES

FAMILY

DESCRIPTION

Also known as NFSB_ECOLI, nfsB, dprA, nfnB, nfsI, ntr. Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2, 4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species. Homodimer.

Also known as NFSB_ECOLI, nfsB, dprA, nfnB, nfsI, ntr. Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons a ...

EXTERNAL LINKS

uniprot
enzyme classification

nfsB

Oxygen-insensitive NAD(P)H nitroreductase

nfsB

Molecular Synopsis