FEATURES

DESCRIPTION

Also known as SAP1_SCHPO, sap1. Binds to sequences required for mating-type switching. Makes a simultaneous contact with both the alpha and beta domains of the switch-activating site SAS1. Also binds to replication fork barrier 1 (RFB1) located within a 78 base pair sequence near the 3' end of the rRNA coding region. This leads to replication fork blockage. It binds the consensus sequence 5'-TA[AG]GCAGNTN[CT]AACG[AC]G-3'., Has a role in chromosome organization and integrity where it is involved in chromosome segregation. Has a role in sister chromatid cohesion and condensation. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

sap1

Mutations

Mutation(s) distribution

Mutations table