FEATURES

FAMILY

DESCRIPTION

Also known as MATK_HUMAN, MATK, CTK, HYL. Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation. Interacts with KIT.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MATK

Megakaryocyte-associated tyrosine-protein kinase

MATK

Molecular Synopsis