FEATURES

FAMILY

DESCRIPTION

Also known as MOB2_YEAST, MOB2. Functions as an activator subunit for the CBK1 protein kinase. Part of the regulation of ACE2 activity and cellular morphogenesis (RAM) signaling network. Required for coordinating polarized cell growth during interphase with the onset of mitosis. Required for mother/daughter cell separation after cytokinesis. Also has a role in the prevention of nuclear export of ACE2 from the daughter cell nucleus after mitotic exit. It coordinates ACE2-dependent transcription with mitotic exit network activation. Interacts with protein kinase CBK1 to form the RAM CBK1-MOB2 kinase complex.

EXTERNAL LINKS

uniprot
enzyme classification

MOB2

Mutations

Mutation(s) distribution

Mutations table