FEATURES

FAMILY

DESCRIPTION

Also known as COPD_YEAST, RET2. The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Interacts with DSL1.

EXTERNAL LINKS

uniprot
enzyme classification

RET2

Mutations

Mutation(s) distribution

Mutations table