FEATURES

FAMILY

DESCRIPTION

Also known as DAPE_HAEIN, dapE. Catalyzes the hydrolysis of N-succinyl-L, L-diaminopimelic acid (SDAP), forming succinate and LL-2, 6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls. It can only hydrolyze L, L-N-succinyl-diaminopimelic acid (L, L-SDAP) and is inactive toward D, L-, L, D-, and D, D-SDAP. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

dapE

Succinyl-diaminopimelate desuccinylase

dapE

Molecular Synopsis