FEATURES

FAMILY

DESCRIPTION

Also known as ACY2_HUMAN, ASPA, ACY2, ASP. Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ASPA

Aspartoacylase

Mutations

Mutation(s) distribution

Mutations table

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