FEATURES

FAMILY

DESCRIPTION

Also known as MMGE_BACSU, mmgE, prpD, yqiP. Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles (PubMed:28956599). Has both 2-methylcitrate dehydratase and citrate dehydratase activities. Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield 2-methyl-cis-aconitate, and the dehydration of citrate to yield cis-aconitate. Cannot form isocitrate. Uses either (2S, 3R)- or (2R, 3S)-2-methylcitrate (PubMed:28956599).

EXTERNAL LINKS

uniprot
enzyme classification

mmgE

Citrate/2-methylcitrate dehydratase

mmgE

Molecular Synopsis