FEATURES

FAMILY

DNA polymerase delta/II small subunit family

DESCRIPTION

Also known as DPOD2_YEAST, POL31, HUS2, HYS2, SDP5. DNA polymerase delta (DNA polymerase III) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair. DNA polymerase delta is a heterotrimer of POL3, POL32 and HYS2.

EXTERNAL LINKS

uniprot
enzyme classification

POL31

Mutations

Mutation(s) distribution

Mutations table